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Medications Tailored to You

No two people are the same. From our looks to our genetic makeup, we’re all distinct. Ever wondered why a treatment works well for some but not for you? The answer might be in your genes. Pharmacogenomics (PGx) reveals how your DNA affects your body’s response to medications.

By analyzing your genetic profile, PGx empowers your healthcare provider to select the most effective medications and dosages designed specifically for you. Say goodbye to frustrating trial-and-error treatments and hello to precision care that aligns with your biology.

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Drug Receptor

Many medications work by binding to specific receptors found on the surface of cells throughout your body. Think of these receptors as tiny locks, and the medication as a key that fits into them. The shape, number, and function of these receptors are determined by your DNA, which means each person’s receptors can vary. If someone’s receptors are shaped differently, are present in different amounts, or are missing altogether, the medication may not work as expected. For example, if the ‘key’ doesn’t fit well into the ‘lock’ or if the ‘lock’ isn’t there, the medication could be less effective, or not work at all. Understanding these differences is important for finding the right treatment for each individual.

Drug Uptake

Some medications work by entering and being absorbed directly into the cells, a process known as 'uptake.' Your DNA plays a key role in determining how quickly and efficiently your cells absorb the medication. If your cells absorb the drug more slowly than the manufacturer intended, the medication might not be effective. Conversely, if your body expels the medication too quickly, it can also impact how well the medication works. Understanding these processes helps ensure that medications are effective and tailored to each individual’s needs.

Drug Metabolism

Your DNA also affects how quickly your body breaks down a medication. If you metabolize the drug faster than average, you might need a higher dose to achieve the desired effect. Conversely, if your body processes the medication more slowly, a lower dose might be sufficient. This personalized approach helps ensure that you get the right amount of medication for optimal results.

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PHARMACOGENOMICS (PGX)

It's as easy as...

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1

Swab

PGx testing is performed using a quick and painless swab of the inner cheek to collect a saliva sample.

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2

Drop

Drop your sample off at a local shipping courier, and it will be sent overnight to our lab for rapid processing.

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3

Result

A detailed report with applicable findings will be e-delivered within 48 hours from when your sample arrives.

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Hospital Admissions

Approximately 1.3 million preventable adverse drug events occur annually in U.S. hospitals, often due to issues such as incorrect dosing or drug interactions.

Medication Errors

Drug-related errors contribute to over 7,000 deaths each year in hospitals, many of which could be mitigated through PGx testing.

Adverse Drug Reactions (ADRs)

ADRs account for 6.7% of hospital admissions and can result in severe complications or extended hospital stays, highlighting the importance of precise medication management.

Benefits of PGx Testing

Pharmacogenomics (PGx) testing tailors medication therapy based on an individual’s genetic profile, significantly enhancing treatment efficacy and reducing the risk of adverse drug reactions (ADRs). This personalized approach helps in optimizing drug dosages, selecting the most effective medications, and preventing severe side effects. Evidence shows that PGx testing improves patient safety, minimizes trial-and-error in medication selection, and leads to better overall health outcomes.

Optimized Dosage

Accurate adjustments to drug dosages based on genetic insights

Enhanced Efficacy

More effective medications tailored to genetic profiles

Reduced ADR Risk

Identification of genetic predispositions to prevent harmful reactions

Prevention of Trial-and-Error

Streamlined treatment choices with actionable genetic data

Improved Safety

Personalized healthcare that enhances overall patient safety

Severe Allergic Recations

Prevention of life-threatening allergies

Toxic Drug Levels

Avoidance of drug toxicity

Ineffective Treatments

Reduction of prolonged illness due to ineffective drugs

Drug Interactions

Minimization of adverse drug interactions

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Pharmacogenetics Associations

Click the button below to view a table detailing pharmacogenetic associations. (FDA)

Pharmacogenomic Biomarkers

Click the button below to view the a table of PGx Biomarkers in Drug Labeling. (FDA)

Primary Care Medicine

Click the button below to view an article discussing PGx in the field of primary care. 

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